Native and Recombinant Fatty Acid Binding Protein 3 fromFasciola Hepaticaas a Potential Antigen
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چکیده
منابع مشابه
Native and Recombinant Fatty Acid Binding Protein 3 from Fasciola Hepatica as a Potential Antigen
Lipid-binding proteins are members of widely distributed protein family. They take part in metabolism of different lipophilic ligands and also have a role in physiological activity, metabolism and disposition of essential hydrophobic compounds (fatty acids, phospholipids, eicosanoids, retinoids, etc.) which are important molecules involved in several cellular processes including gene transcript...
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Fatty acid binding protein (FADP) is an attractive vaccine candidate and a drug target for controlling fasciolosis caused by Fasciola gigantica in ruminants. The cDNA encoding F. gigantica FADP was amplified by polymerase chain reaction and expressed in Escherichia coli as a recombinant protein using a prokaryotic expression system. The protein was purified to homogeneity by nickel chelating af...
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This article reviews our current understanding of the uptake of fatty acids by the enterocytes of the intestine. The micellar solubilization of fatty acids by bile salts and the factors regulating that process are discussed. The mechanism of how micellar solubilization of fatty acids promotes the uptake of fatty acids by enterocytes and their relative importance is reviewed. Additionally, discu...
متن کاملFatty acid-binding protein from embryonic chick retina resembles mammalian heart fatty acid-binding protein.
PURPOSE Fatty acid-binding proteins (FABP) make up a family of cytosolic proteins of unknown function found in many tissues, including the embryonic chick retina. To further understand its function in the developing retina, the protein from embryonic chicks was purified and characterized. The tissue distribution of this protein in embryonic and hatched chicks was determined using polyclonal ant...
متن کاملPolyene fatty acid interactions with recombinant intestinal and liver fatty acid-binding proteins. Spectroscopic studies.
Binding and proximity relationships of fatty acids with recombinant rat liver fatty acid-binding protein (L-FABP) and intestinal fatty acid-binding protein (I-FABP) were studied with absorption and fluorescence spectroscopy. Protein aromatic amino acids were examined in the absence and presence of bound fatty acid. Second derivative absorbance spectroscopy of the apo- and holoproteins suggested...
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ژورنال
عنوان ژورنال: Biotechnology & Biotechnological Equipment
سال: 2012
ISSN: 1310-2818,1314-3530
DOI: 10.5504/50yrtimb.2011.0011